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Genetically engineered resistance to African Cassava Mosaic Virus (ACMV) in cassava
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| Coordinating organisation: | Institute of Plant Sciences |
| Description: | African cassava mosaic disease (ACMD) is the most serious disease threatening cassava production in Africa at present. The losses caused by ACMD throughout the continent are 40%, and locally the harvests can be lost completely. ACMD is caused by the geminivirus African cassava mosaic virus (ACMV) and transmitted by whiteflies (Bemisia tabaci). ACMV has circular single-stranded DNA (ssDNA) denoted DNA A and B, which is encapsidated in twin icosahedral particles. No cassava variety completely resistant to ACMV could so far be produced by traditional breeding. e want to engineer resistance against the African Cassava Mosaic Virus (ACMV) using two different approaches and to study the effectiveness of these methods in conferring cassava resistant against ACMV. The first approach involves expression of antisense RNAs as 3' untranslated regions of a selectable marker gene. The second approach relies on mimicking the hypersensitive reaction (HR) of incompatible host-pathogen interactions by taking advantage of the regulation of the ACMV promoters. The ultimate goal is to produce transgenic cassava plants resistant to ACMV in the field. |
| Internet: | Projects Link |
| Start: | 1997-06-30 |
| End: | 2010-12-31 |
| Species: | Cassava |
| Total number of staff: | 4 |
| Number of staff abroad: | 1 |
| Categories | |
| ARD-theme: | plant genetic resources plant breeding plant protection/IPM |
| Target country: | Colombia Germany Nigeria Switzerland |
| Commodity: | root/tuber |
| Ecosystem: | humid tropical |
| Activity: | research |
| Registered related items | |
| Participating organisations: | 3 |
| Last editing: | 2005-11-11 13:17:42 |